Tag Archive for: wine

Better Hops & Perfect Wine


Agricultural geneticist and self-proclaimed “craft beer fanatic”, Sean Myles began breeding hops plants that are resistant to mildew. Other breweries are now using traditional breeding techniques to breed hopes varieties with novel flavors, changing the craft beer game. For wine lovers, there’s Linda Bisson, a yeast geneticist at UC Davis working on the winemaking issue of “stuck” fermentation, a phenomenon when yeast added to wine fail to fully ferment.
Read more

Cooking Wines & Cultured Meats


One ambitious cook aims to settle if wine quality affects wine dishes, while an equally ambitious researcher attempts to create a lab-grown hamburger.
Read more

Food, Wine, and Biochemistry

Photo Credit: Kirti Poddar (22598380@N07/Flickr)

Photo Credit: Kirti Poddar (22598380@N07/Flickr)

Wine and food pairing may seem like a refined art form, cultivated through trial and error to best suit the individual, but what if we told you there was also a science to it?

When it comes to wines, the word “tannin” is thrown around a lot. In broad terms, tannins are a type of flavonoid molecule, which reside in the bark, leaves, and unripe fruits of a wide variety of plants. The three major classes of tannins are hydrolyzable, condensed, and phlorotannins. Where wine is concerned, phlorotannins are nonexistent (only found in brown algae); hydrolyzable tannins leach from the oak barrel that wines have fermented and aged in; and condensed tannins come from the grapes [1]. While hydrolyzable tannins may be present in all wines, since winemaking traditions necessitate oak barrels, these offer little towards wine taste, mouthfeel, and color. Viniculture favors condensed tannins. Originating from the grape skins, seeds, and stems that go into winemaking, condensed tannins play a key role in wine-tasting.

Red wines are made using the entire wine grape, obtaining their color from anthocyanin, another type of flavonoid molecule found alongside tannins in grape skins. By contrast, white wines are produced from just the grape pulp. Since the tannin-containing parts of the grape do not go into white wine production, white wines are often lower in tannin levels and generally lack condensed tannins.

So how is all this discussion about tannins relevant in choosing which wine to serve alongside a steak dinner?

Tannins contribute to two wine-tasting characteristics: bitterness and astringency [1,3]. Anyone who has ever eaten an under-ripe grape has experienced an exaggerated sensation of astringency, as under-ripe grape skins contain high tannin concentrations. However, astringency should not be confused with bitterness or sourness; these tastes are perceived on the tongue through bitter and sour taste receptors. Conversely, astringency is a physical sensation, frequently described as a dryness or roughness on the tongue.

A sip of wine is just the beginning of the biochemical process behind astringency. Our saliva contains proteins that are able to organize water molecules about themselves, which increases saliva viscosity to above water viscosity, giving rise to “mouth lubrication” [2]. Tannins in wine readily bind to saliva proteins. This causes a snowball effect: tannin-bound proteins end up clumping together with other tannin-bound proteins, creating an aggregate [3]. This aggregate inevitably precipitates out of our saliva. With fewer free, unbound saliva proteins, there is a decrease in saliva viscosity, subsequently leading to a decrease in mouth lubrication [3]. In short, tannins physically dry out the tongue.

In this respect, high-tannic red wines pair well with high-protein foods. With more tannins binding to food proteins, saliva proteins are spared and the wine doesn’t feel as astringent in the mouth. Tried-and-true pairings include Cabernet Sauvignon with a rack of lamb, Pinot Noir with pork roast, and Chianti with grilled salmon.

Besides the protein interactions, tannins have also been shown to favorably bind to fats [4]. Fats are polar molecules by nature (they don’t like to interact with water). On the other hand, saliva is mostly water. By attaching to tannins, fats hinder tannins from mixing with saliva and binding to proteins. Essentially, fats wash the tannins away. For this reason, wine paired with cheese is a great treat, as is a gourmet burger with a glass of Zinfandel.

Armed with this knowledge, why not begin your own wine and food adventure? May we suggest a Cabernet with mac and cheese with spam?

Photo Credit: Jose Tagarao (lidocaineus/Flickr)

References cited

  1. Goode, Jamie. “Tannins in Wine.”Wine Anorak.
  2. Hatton M, et al. Lubrication and viscosity features of human saliva and commercially available saliva substitutes. Journal of Oral and Maxillofacial Surgery. June 1987;45(6):96-99.
  3. Cala O, et al. NMR and molecular modeling of wine tannins binding to saliva proteins: revisiting astringency from molecular and colloidal prospects. The FASEB Journal. November 2010;24(11):81-90.
  4. Furlan, A, et al. Red wine tannins fluidify and precipitate lipid liposomes and bicelles. A role for lipids in wine tasting? Langmuir. May 2014;30(19):18-26.

Alice PhungAbout the author: Alice Phung once had her sights set on an English degree, but eventually switched over to chemistry and hasn’t looked back since.

Read more by Alice Phung

The Science of Champagne Bubbles

Photo credit: _FXR/Flickr

Photo credit: _FXR/Flickr

Toast the new year with a bottle of champagne! With its effervescent fizz, golden sparkle, and showy corking, it is the go-to celebratory drink. Read up on champagne making, bubble formation, and the mathematics behind bubble patterns, and get ready to show off some foodie knowledge at this winter’s new year’s party.

How It’s Made

A sparkling wine isn’t champagne unless it comes from its namesake region of France. The Champagne province in the northeast of France boasts ideal soil conditions which contribute to the grape quality, and thus the quality of the beverage that results from champagne winemaking.

Champagne undergoes a two-part fermentation process. The first fermentation results in a flat champagne wine. Next, yeast and sugar are added to this base, and the bottle is sealed. The yeast consume the sugar and produce alcohol along with about 10 grams of CO2 per liter of fluid [1].

Toward the end of production the bottle is opened, whereupon the yeast and about 80% of the CO2 are expelled from the bottle. It may seem that allowing such a large fraction of the CO2 to escape would be undoing the yeast’s hard work, but the remaining 20% in the fluid are enough to make 20 million bubbles in one champagne flute, each no larger than a millimeter in diameter [1]. The bottle is quickly corked once again, and is then ready to be sold.

The Pop

Photo credit: BitHead/Flickr

Photo credit: BitHead/Flickr

At 11:59 on December 31st, many will have a bottle in hand and will be anticipating the bang of the cork shooting out; this is caused by the buildup of pressure inside the bottle. Surprisingly, only 5% of the energy exerted during the bottle opening is the cork’s kinetic energy, that is, the energy of motion that would propel the cork into your uncle’s eye. The remaining 95% of the energy generates the popping sound’s shock wave. This wave causes a mushroom cloud-like pattern of CO2 that is released when the cork pops [3]. The white fog that rises from the bottle after the mushroom cloud is a mist of ethanol and water vapor, triggered by the sudden drop in gas temperature when the bottle pressure is rapidly released Because of the speed at which this occurs, there is no time for the energy transfer—heating—to occur. The result is adiabatic cooling. The gas temperature drops, causing the water vapor in the gas to condense [3].

The Bubbles

Natural Effervescence — Champagne fizz has a rather surprising source. It is caused by the presence of tiny cellulose fibers that cling to the glass by electrostatic forces. The fibers are deposited from the air or that have been left over after wiping the glass with a towel. Each fiber, about 100 micrometers long, develops an internal gas pocket as the glass is filled. These microfiber gas pockets are the bubble formation sites. To form a bubble, dissolved CO2 has to push through liquid molecules held together by very weak but abundant molecular interactions. The CO2 would not have enough energy to do this on its own, but the gas pockets held in the cellulose fibers lower the energy barrier and allow a bubble to form. CO2 continually deposits itself from the champagne into the bubble until it reaches about 10-50 micrometers [1], whereupon its buoyant force is so great that it detaches from the fiber and floats upward. A new bubble forms immediately in its place.

Artificial Nucleation — Because natural effervescence is very random and not easily controlled, glassmakers use a more reproducible way to generate bubbles. Glassmakers use a laser to engrave artificial nucleation sites at the bottom of the glass to make the effervescence pattern pleasing to the eye. They usually create no fewer than 20 scratches to create a ring shape, which produces a consistent column of rising bubbles.

Bubble Patterns

Bubbling patterns actually change over the time that the champagne is within the glass. The bubbles start out as strings that rise in pairs, then gradually transition to bubbles in groups of threes, and finally settle down in a clockwork pattern of regularly spaced individual bubbles. A team of physicists in the Champagne region of France have performed extensive research to figure out the science behind champagne fizz and the interesting patterns the bubble strings form.

The patterns are determined by the vibration rate of the gas trapped at the nucleation point and the growth rate of the bubbles outside. These factors are determined by  atmospheric pressure on the surface of the champagne, temperature, and the size of the nucleation point in the glass, among other factors. The Champagne team has arrived upon a complex equation to explain the differential patterns of bubble streams by relating bubble radius, oscillation frequency of the gas pocket, and the time interval between two successive bubbles [2]

R(Ti + 1) = Ro + Ecos(2πωFbTi + 1)

where Ro is the radius of the bubble just before release, and Ti is the time interval between two successive bubbles, ω is the ratio between the oscillation frequencies of the gas pocket and the bubble (Fb), and E is related to the interactions between the two systems [2].

Now that some of the mystery behind the sparkle and pop of champagne has been explained through science, opportunities to impress friends and strike up conversation present themselves at the next big occasion. Break out a timer and graph paper; observe one nucleation point on a glass and measure the transition time from two to three bubble patterns. Someone is bound to ask what the stop watch is for.


  1. “Bubbles and Flow Patterns in Champagne.”  American Scientist. N.p., n.d. Web. 19 Dec. 2013.
  2. Liger-Belair, Gerard. “Period Adding Route in Sparkling Bubbles.” Physical Review 72 (2005): n. pag. Web.
  3. Boyle, Alan. “The Science of Champagne Bubbles Up for Again For News Year’s Eve.” NBC News. N.p., 31 Dec. 2012.

Elsbeth SitesAbout the author: Elsbeth Sites is pursuing her B.S. in Biology at UCLA. Her addiction to the Food Network has developed into a love of learning about the science behind food.

Read more by Elsbeth Sites